What Are Peptides and Ceramides and Why Your Skin Needs Them

Peptides are short chains of amino acids (protein fragments) that stimulate skin cells. They increase collagen and elastin production, speed up skin regeneration, reduce the appearance of wrinkles, and improve firmness. Peptides act as “messenger molecules” for fibroblasts and other skin cells, signaling them to produce essential structural proteins.

Ceramides are lipids (fats) naturally present in the skin’s stratum corneum, forming the foundation of its barrier function. Ceramides help retain moisture, restore the lipid barrier, and protect the skin from irritants and water loss. As we age, ceramide levels decrease, so topical ceramide application helps restore the barrier, reduce dryness, and prevent irritation.

Why the Combination of Peptides + Ceramides Is a Great Idea

Peptides work on the structure of the skin (collagen stimulation, lifting effect, regeneration), while ceramides work on the barrier (protection and moisture retention). 

Together, they strengthen the skin from within and protect it from the outside, reducing dryness, improving texture, enhancing firmness, and minimizing the appearance of wrinkles. 

Scientific literature confirms the anti-aging benefits of peptides and the barrier and moisturizing benefits of ceramides.

How Peptides and Ceramides Work on the Face — Explained Simply

Peptides signal skin cells, “It’s time to produce collagen and hyaluronic acid,” which increases dermal density. 

Ceramides “seal in” moisture and restore the lipid “brick-like” structure of the stratum corneum, reducing dryness and making the skin smoother and more even. 

The result is less noticeable wrinkles, a more even tone, and overall comfort.

Who Benefits Most (Skin Type and Age Recommendations)

• Dry, dehydrated, and sensitive skin — prioritize ceramides daily.
• Mature skin (30+, 40+) or skin showing signs of sagging — peptides are recommended (use a 6–12 week course for visible results).
• Combination skin — use a peptide serum with a ceramide moisturizer.
• Problematic or inflamed skin — focus on ceramides to restore the barrier; peptides can be added under professional guidance.

How Long and How Often to Use (Program / Course)

• Ceramides: safe for daily and long-term use (AM and/or PM), can be included in your basic moisturizer permanently.
• Peptides: cumulative effect — noticeable changes usually appear after 6–12 weeks of consistent use (at least 8 weeks recommended). Morning or evening application is flexible, depending on the formula (serum or cream).
• Ampoule Courses (e.g., BABOR concentrates/ampoules): typically 7–14 days, providing a fast “lifting” effect. Can be repeated as per instructions. BABOR notes visible results within 7 days for certain ampoules.

How to Read Labels: What to Look For

Check INCI/ingredient lists for:

• Ceramides: Ceramide NP, AP, EOP, NS, Sphingolipids, Sphingomyelin
• Peptides: Palmitoyl tripeptide, Palmitoyl tetrapeptide, Acetyl hexapeptide, Hydrolyzed lupine protein, Tripeptide

If a product contains both, it’s a combined formula. If not, combine a peptide serum with a ceramide cream for optimal results.

Trusted Peptide and Ceramide Products from Israeli Brand Christina

1. Nuance Pro-Collagen Vitality Cream

This cream from the Nuance line contains Collagen Amino Acids (biomimetic peptides) and Phyto-Ceramide Complex (a plant-based complex with Ceramide 3). It is suitable for mature, dehydrated skin, targeting firmness, radiance, and barrier restoration.

• Usage: Apply daily; visible results typically appear after 6–12 weeks.
• Additional benefit: Ceramides in the formula make it safe for ongoing daily use.

Source: Official Christina product page.

2. BioPhyto Line

Highlighted products include BioPhyto Absolute Detox Serum and BioPhyto Zaatar / Zaatar Cream. The BioPhyto line features Phyto-Ceramide Complex alongside Anti-Toxins Peptides and other peptide complexes. This combination is excellent for skin with a compromised barrier, inflammation, or environmental stress. A recommended routine is pairing a peptide serum with a BioPhyto ceramide cream.

Source: BioPhyto line description on the official Christina website.

3. Forever Young / Moisture Fusion (Serums and Creams)

Products in the Forever Young line contain various peptides (e.g., lift-peptides, tripeptides) that boost hydration and stimulate the skin’s own hyaluronic acid production. For full barrier restoration, these can be combined with a ceramide-rich BioPhyto cream.

Source: Forever Young product pages on the official Christina website.

Comment on Christina products:

Many products on the official site clearly list Phyto-Ceramide and peptide complexes. Some creams and serums contain both active ingredients in one formula, while others contain only one. For stronger effects, it is often more practical to pair a peptide serum with a ceramide cream.

BABOR: Ampoule Programs for Peptides and Ceramides

BABOR offers specialized ampoule programs (Power Serum Ampoules) that include both peptide ampoules (e.g., Hyaluronic + Tripeptides) and ceramide ampoules within the same set. 

This approach is convenient, as it delivers both structural and barrier benefits in a short course. BABOR notes that some ampoules provide visible results in as little as 7 days when used as directed in a course.

How to Choose and Combine Products

• All-in-one option: Look for creams or serums that contain both peptides and ceramides in the formula (available in some Christina products and selected BABOR ampoules).
• If a combined product isn’t available:
  • Morning: Ceramide cream/serum + SPF
  • Evening: Peptide serum + richer ceramide cream
• Ampoule courses (BABOR): Typically 7–14 days, followed by a break or maintenance with a cream. Courses can be repeated 2–3 times per year or as recommended by a skincare professional.

Safety and Compatibility with Other Actives

• Ceramides: Safe and rarely irritating, suitable for daily use.
• Peptides: Generally well tolerated; effects are cumulative. When using aggressive acids or retinoids, alternate applications (morning/evening) or separate by days for sensitive skin.
• Always perform a patch test with new products, and consult a dermatologist if you have a skin condition.

Quick Guide for Choosing the Best Peptide + Ceramide Moisturizer

When selecting a moisturizer with peptides and ceramides, look for products that contain Ceramide NP/AP/EOP or Sphingolipids, along with Palmitoyl Tripeptide, Hydrolyzed Lupine Protein, Acetyl Hexapeptide, or another peptide ingredient.

• For dry or sensitive skin: prioritize ceramides.
• For mature or sagging skin: add peptides.
• Ampoules: ideal for short-term, intensive courses for fast results.

Where to Buy

You can find all these verified products on our website: https://www.miamibeautyarea.com/shop/

If you’re unsure which product to choose, I offer personalized skincare consultations (online or via chat). During the consultation, I will select the optimal combination (peptide serum + ceramide cream or an ampoule course), explain the application routine, and recommend course duration. 

Contact us, and I will create an individualized skincare plan just for you.